AntiVirus Internet Security recommendations request

Over the past few years I've used McAfee with W95. NAV w/ W98. NAV
corp 7.0 with W2K. Trend Micro with XP (subscription is now over) and
Panda Titanium which I'm not crazy about.

I want your input on which new suites are best as far as not causing
too much problems, slowing down normal operation, and of course
effective at stopping infection and removing viruses. I do plenty of
websurfing and downloading.

Thanks